{"id":1201,"date":"2026-05-12T15:05:42","date_gmt":"2026-05-12T15:05:42","guid":{"rendered":"https:\/\/pathology.digital\/?p=1201"},"modified":"2026-05-12T15:06:36","modified_gmt":"2026-05-12T15:06:36","slug":"path2space-breast-cancer-spatial-transcriptomics","status":"publish","type":"post","link":"https:\/\/pathology.digital\/?p=1201","title":{"rendered":"Path2Space: \u062a\u0648\u0642\u0639 \u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0645\u0643\u0627\u0646\u064a \u0645\u0646 \u0634\u0631\u0627\u0626\u062d \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a"},"content":{"rendered":"<article dir=\"rtl\" lang=\"ar\">\n<p>\u0646\u0634\u0631\u062a \u0645\u062c\u0644\u0629 <em>Cell<\/em> \u062f\u0631\u0627\u0633\u0629 \u0628\u0639\u0646\u0648\u0627\u0646 <a href=\"https:\/\/doi.org\/10.1016\/j.cell.2026.04.023\" target=\"_blank\" rel=\"noopener\">AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology<\/a> \u062a\u0642\u062a\u0631\u062d \u0645\u0633\u0627\u0631\u0627\u064b \u0639\u0645\u0644\u064a\u0627\u064b \u0644\u062a\u0648\u0633\u064a\u0639 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u0643\u0627\u0646\u064a\u0629 \u0641\u064a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0645\u0646 \u062f\u0648\u0646 \u0625\u062c\u0631\u0627\u0621 spatial transcriptomics \u0644\u0643\u0644 \u0639\u064a\u0646\u0629. \u0627\u0644\u0641\u0643\u0631\u0629 \u0627\u0644\u0645\u0628\u0627\u0634\u0631\u0629: \u0646\u0645\u0648\u0630\u062c \u0639\u0645\u064a\u0642 \u0628\u0627\u0633\u0645 <strong>Path2Space<\/strong> \u064a\u062a\u0639\u0644\u0645 \u0645\u0646 \u0634\u0631\u0627\u0626\u062d \u0627\u0644\u0647\u0633\u062a\u0648\u0628\u0627\u062b\u0648\u0644\u0648\u062c\u064a \u0627\u0644\u0645\u0642\u062a\u0631\u0646\u0629 \u0628\u0628\u064a\u0627\u0646\u0627\u062a ST\u060c \u062b\u0645 \u064a\u062a\u0646\u0628\u0623 \u0628\u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0645\u0643\u0627\u0646\u064a \u0645\u0628\u0627\u0634\u0631\u0629 \u0645\u0646 \u0627\u0644\u0635\u0648\u0631\u0629.<\/p>\n<p>\u0647\u0630\u0627 \u0627\u0644\u0646\u0648\u0639 \u0645\u0646 \u0627\u0644\u0639\u0645\u0644 \u064a\u0647\u0645 \u0627\u0644\u0628\u0627\u062b\u0648\u0644\u0648\u062c\u064a \u0627\u0644\u0631\u0642\u0645\u064a \u0644\u0623\u0646\u0647 \u0644\u0627 \u064a\u062a\u0639\u0627\u0645\u0644 \u0645\u0639 \u0627\u0644\u0634\u0631\u064a\u062d\u0629 \u0643\u0635\u0648\u0631\u0629 \u062a\u0635\u0646\u064a\u0641\u064a\u0629 \u0641\u0642\u0637. \u0627\u0644\u0647\u062f\u0641 \u0647\u0646\u0627 \u0644\u064a\u0633 \u0627\u0644\u062a\u0646\u0628\u0624 \u0628\u062f\u0631\u062c\u0629 \u0627\u0644\u0648\u0631\u0645 \u0623\u0648 subtype \u062c\u0627\u0647\u0632\u060c \u0628\u0644 \u0628\u0646\u0627\u0621 \u0637\u0628\u0642\u0629 \u062c\u0632\u064a\u0626\u064a\u0629 \u0645\u0643\u0627\u0646\u064a\u0629 \u0645\u062a\u0648\u0642\u0639\u0629 \u0641\u0648\u0642 \u0627\u0644\u0646\u0633\u064a\u062c\u060c \u0628\u062d\u064a\u062b \u062a\u0635\u0628\u062d \u0628\u0646\u064a\u0629 \u0627\u0644\u0648\u0631\u0645 \u0648\u0627\u0644\u0640 TME \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u062d\u0644\u064a\u0644 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0623\u0641\u0648\u0627\u062c \u0643\u0628\u064a\u0631\u0629 \u0644\u0627 \u064a\u0645\u0643\u0646 \u0639\u0645\u0644\u064a\u0627\u064b \u0641\u062d\u0635\u0647\u0627 \u0643\u0644\u0647\u0627 \u0628\u062a\u0642\u0646\u064a\u0627\u062a ST \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0643\u0644\u0641\u0629.<\/p>\n<p>\u0627\u0644\u0641\u0631\u0642 \u0639\u0646 \u0643\u062b\u064a\u0631 \u0645\u0646 \u0646\u0645\u0627\u0630\u062c WSI \u0627\u0644\u0633\u0627\u0628\u0642\u0629 \u0623\u0646 \u0627\u0644\u0645\u062e\u0631\u062c \u0644\u064a\u0633 label \u0648\u0627\u062d\u062f\u0627\u064b \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0634\u0631\u064a\u062d\u0629 \u0623\u0648 tile. \u0627\u0644\u0645\u062e\u0631\u062c \u062e\u0631\u064a\u0637\u0629 \u062a\u0639\u0628\u064a\u0631\u060c \u0623\u064a \u0623\u0646 \u0627\u0644\u0633\u0624\u0627\u0644 \u064a\u0646\u062a\u0642\u0644 \u0645\u0646 &#8220;\u0645\u0627\u0630\u0627 \u064a\u0648\u062c\u062f \u0641\u064a \u0627\u0644\u0639\u064a\u0646\u0629\u061f&#8221; 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testing.<\/p>\n<h2>\u0627\u0644\u062e\u0644\u0627\u0635\u0629<\/h2>\n<p>Path2Space \u064a\u0642\u062f\u0645 \u0645\u062b\u0627\u0644\u0627\u064b \u0646\u0627\u0636\u062c\u0627\u064b \u0639\u0644\u0649 \u0627\u062a\u062c\u0627\u0647 \u0645\u0647\u0645 \u0641\u064a \u0627\u0644\u0628\u0627\u062b\u0648\u0644\u0648\u062c\u064a \u0627\u0644\u0631\u0642\u0645\u064a: \u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0634\u0631\u0627\u0626\u062d \u0627\u0644\u0631\u0648\u062a\u064a\u0646\u064a\u0629 \u0625\u0644\u0649 \u062e\u0631\u0627\u0626\u0637 \u062c\u0632\u064a\u0626\u064a\u0629 \u0645\u0643\u0627\u0646\u064a\u0629 \u0645\u062a\u0648\u0642\u0639\u0629. \u0627\u0644\u0648\u0631\u0642\u0629 \u0644\u0627 \u062a\u063a\u0644\u0642 \u0645\u0644\u0641 spatial transcriptomics\u060c \u0644\u0643\u0646\u0647\u0627 \u062a\u0642\u062a\u0631\u062d \u0637\u0631\u064a\u0642\u0629 \u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 ST \u0643\u0628\u064a\u0627\u0646\u0627\u062a \u062a\u062f\u0631\u064a\u0628 \u062b\u0645 \u062a\u0639\u0645\u064a\u0645 \u0628\u0639\u0636 \u0625\u0634\u0627\u0631\u0627\u062a\u0647\u0627 \u0639\u0644\u0649 \u0623\u0641\u0648\u0627\u062c H&#038;E \u0643\u0628\u064a\u0631\u0629. \u0625\u0630\u0627 \u0635\u0645\u062f\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0641\u064a \u0627\u0644\u062a\u062d\u0642\u0642 \u0627\u0644\u062e\u0627\u0631\u062c\u064a\u060c \u0641\u0642\u062f \u062a\u0635\u0628\u062d \u0647\u0630\u0647 \u0627\u0644\u0645\u0642\u0627\u0631\u0628\u0629 \u0623\u062f\u0627\u0629 \u0642\u0648\u064a\u0629 \u0644\u0627\u0643\u062a\u0634\u0627\u0641 biomarkers \u0639\u0644\u0627\u062c\u064a\u0629 \u0641\u064a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a\u060c \u0648\u0631\u0628\u0645\u0627 \u0641\u064a \u0623\u0648\u0631\u0627\u0645 \u0623\u062e\u0631\u0649 \u0644\u0627\u062d\u0642\u0627\u064b.<\/p>\n<p><strong>\u0627\u0644\u0645\u0635\u062f\u0631:<\/strong> Shulman ED \u0648\u0622\u062e\u0631\u0648\u0646. <em>Cell<\/em>. 2026. DOI: 10.1016\/j.cell.2026.04.023.<\/p>\n<\/article>\n","protected":false},"excerpt":{"rendered":"\u062f\u0631\u0627\u0633\u0629 Cell \u062a\u0639\u0631\u0636 Path2Space \u0644\u0644\u062a\u0646\u0628\u0624 \u0628\u0627\u0644\u062a\u0639\u0628\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0645\u0643\u0627\u0646\u064a \u0645\u0646 \u0634\u0631\u0627\u0626\u062d \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a\u060c \u0648\u0631\u0628\u0637 \u062e\u0631\u0627\u0626\u0637 TME \u0628\u0627\u0644\u0628\u0642\u0627\u0621 \u0648\u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0644\u0644\u0639\u0644\u0627\u062c.","protected":false},"author":1,"featured_media":1200,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"csco_singular_sidebar":"","csco_page_header_type":"","csco_page_load_nextpost":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4],"tags":[],"class_list":{"0":"post-1201","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-news","8":"cs-entry"},"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/pathology.digital\/wp-content\/uploads\/2026\/05\/featured_17091.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts\/1201","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1201"}],"version-history":[{"count":1,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts\/1201\/revisions"}],"predecessor-version":[{"id":1202,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts\/1201\/revisions\/1202"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/media\/1200"}],"wp:attachment":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1201"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}