AI driven pre-regulatory validation of PD-L1 analysis in lung cancer<\/a>. \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0644\u064a\u0633\u062a \u0625\u0639\u0644\u0627\u0646\u0627\u064b \u0639\u0646 \u0628\u062f\u064a\u0644 \u0644\u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636. \u0642\u064a\u0645\u062a\u0647\u0627 \u0623\u0646\u0647\u0627 \u062a\u062e\u062a\u0628\u0631 \u0645\u0633\u0627\u0631\u0627\u064b \u0639\u0645\u0644\u064a\u0627\u064b \u0644\u0623\u062f\u0627\u0629 \u062a\u0639\u0644\u0645 \u0639\u0645\u064a\u0642 \u062a\u0633\u0627\u0639\u062f \u0641\u064a \u062a\u0642\u062f\u064a\u0631 TPS\u060c \u062b\u0645 \u062a\u0639\u064a\u062f \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0642\u0631\u064a\u0628\u0629 \u0645\u0646 \u0639\u062a\u0628\u0627\u062a \u0627\u0644\u0642\u0631\u0627\u0631 \u0625\u0644\u0649 \u0627\u0644\u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u0644\u064a\u062f\u0648\u064a\u0629. \u0647\u0630\u0627 \u0641\u0631\u0642 \u0645\u0647\u0645.<\/p>\n\u0641\u064a \u0627\u0644\u0645\u062e\u062a\u0628\u0631 \u0627\u0644\u062d\u0642\u064a\u0642\u064a\u060c \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u0644\u0627 \u062a\u0643\u0648\u0646 \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0648\u0627\u0636\u062d\u0629 \u0641\u0642\u0637. \u0627\u0644\u0645\u0634\u0643\u0644\u0629 \u0641\u064a \u0627\u0644\u0634\u0631\u064a\u062d\u0629 \u0627\u0644\u062a\u064a \u062a\u0642\u0641 \u0639\u0644\u0649 \u0627\u0644\u062d\u0627\u0641\u0629: \u0647\u0644 \u0647\u064a \u0623\u0642\u0644 \u0645\u0646 1% \u0623\u0645 \u0623\u0639\u0644\u0649 \u0628\u0642\u0644\u064a\u0644\u061f \u0647\u0644 \u062a\u0642\u0639 \u062d\u0648\u0644 50% \u0623\u0645 \u062f\u0627\u062e\u0644 \u0645\u0646\u0637\u0642\u0629 40 \u0625\u0644\u0649 60% \u0627\u0644\u062a\u064a \u064a\u0635\u0639\u0628 \u062d\u0633\u0645\u0647\u0627 \u0628\u062b\u0642\u0629\u061f \u0647\u0646\u0627 \u064a\u0635\u0628\u062d \u0627\u0644\u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u0631\u0642\u0645\u064a \u0627\u0644\u062c\u064a\u062f \u0645\u0641\u064a\u062f\u0627\u064b\u060c \u0628\u0634\u0631\u0637 \u0623\u0646 \u064a\u062d\u062a\u0631\u0645 \u062d\u062f\u0648\u062f \u0627\u0644\u0641\u062d\u0635 \u0648\u062d\u062f\u0648\u062f \u0627\u0644\u0635\u0648\u0631\u0629 \u0648\u062d\u062f\u0648\u062f \u0627\u0644\u0639\u064a\u0646\u0629.<\/p>\n
\u0645\u0627 \u0627\u0644\u0630\u064a \u0641\u0639\u0644\u0647 \u0627\u0644\u0641\u0631\u064a\u0642\u061f<\/h2>\n
\u0627\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 1100 \u0635\u0648\u0631\u0629 \u0631\u0642\u0645\u064a\u0629 \u0645\u062c\u0647\u0648\u0644\u0629 \u0627\u0644\u0647\u0648\u064a\u0629 \u0644\u0635\u0628\u063a\u0629 PD-L1 \u0641\u064a \u0639\u064a\u0646\u0627\u062a NSCLC \u0645\u062b\u0628\u062a\u0629 \u0628\u0627\u0644\u0641\u0648\u0631\u0645\u0627\u0644\u064a\u0646 \u0648\u0645\u0637\u0645\u0648\u0631\u0629 \u0628\u0627\u0644\u0628\u0627\u0631\u0627\u0641\u064a\u0646\u060c \u0645\u0639 1100 \u0635\u0648\u0631\u0629 H&E \u0645\u0642\u0627\u0628\u0644\u0629. \u062c\u0627\u0621\u062a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0645\u0646 \u0633\u064a\u0631 \u0639\u0645\u0644 \u062a\u0634\u062e\u064a\u0635\u064a \u0631\u0648\u062a\u064a\u0646\u064a \u0641\u064a \u0623\u064a\u0631\u0644\u0646\u062f\u0627 \u0627\u0644\u0634\u0645\u0627\u0644\u064a\u0629\u060c \u0648\u0634\u0645\u0644\u062a adenocarcinoma \u0648squamous cell carcinoma\u060c \u0645\u0646 \u062e\u0632\u0639\u0627\u062a \u0648\u0627\u0633\u062a\u0626\u0635\u0627\u0644\u0627\u062a. \u0627\u0633\u062a\u064f\u062e\u062f\u0645 \u0627\u062e\u062a\u0628\u0627\u0631 Ventana Roche SP263\u060c \u0648\u0645\u064f\u0633\u062d\u062a \u0627\u0644\u0634\u0631\u0627\u0626\u062d \u0639\u0644\u0649 Aperio AT2 \u0628\u0635\u064a\u063a\u0629 SVS.<\/p>\n
\u0644\u0644\u062a\u062f\u0631\u064a\u0628 \u0648\u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u060c \u0627\u062d\u062a\u064f\u0641\u0638\u062a \u0645\u062c\u0645\u0648\u0639\u0629 \u0645\u0646 396 \u062d\u0627\u0644\u0629 \u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0646\u0645\u0648\u0630\u062c. \u0642\u064f\u0633\u0645\u062a \u0625\u0644\u0649 \u062a\u062f\u0631\u064a\u0628 \u0628\u0646\u0633\u0628\u0629 65%\u060c \u0648\u062a\u062d\u0642\u0642 \u0628\u0646\u0633\u0628\u0629 16%\u060c \u0648\u0627\u062e\u062a\u0628\u0627\u0631 \u0628\u0646\u0633\u0628\u0629 19%. \u0648\u0645\u0646 \u0628\u064a\u0646 \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0627\u062a\u060c \u0648\u064f\u062c\u062f\u062a 131 \u062d\u0627\u0644\u0629 \u0628\u064a\u0646 1 \u064849%\u060c \u0648127 \u062d\u0627\u0644\u0629 \u0639\u0646\u062f 50% \u0641\u0623\u0643\u062b\u0631. \u0647\u0630\u0647 \u0627\u0644\u062a\u0641\u0627\u0635\u064a\u0644 \u0645\u0647\u0645\u0629 \u0644\u0623\u0646 \u0623\u062f\u0627\u0629 TPS \u0644\u0627 \u062a\u064f\u062e\u062a\u0628\u0631 \u062c\u064a\u062f\u0627\u064b \u0625\u0630\u0627 \u063a\u0627\u0628\u062a \u0639\u0646\u0647\u0627 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062a\u064a \u062a\u0642\u0639 \u0642\u0631\u0628 \u0639\u062a\u0628\u0627\u062a \u0627\u0644\u062a\u0642\u0631\u064a\u0631.<\/p>\n
\u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0627\u0639\u062a\u0645\u062f \u0639\u0644\u0649 U-Net \u0645\u0639 backbone \u0645\u0646 \u0646\u0648\u0639 ResNet34. \u0627\u0644\u0647\u062f\u0641 \u0644\u0645 \u064a\u0643\u0646 \u0625\u062e\u0631\u0627\u062c \u062f\u0631\u062c\u0629 \u0625\u062c\u0645\u0627\u0644\u064a\u0629 \u0641\u0642\u0637\u060c \u0628\u0644 \u062a\u0642\u0633\u064a\u0645 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0648\u0631\u0645\u064a\u0629 \u0625\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0648\u0633\u0644\u0628\u064a\u0629 \u0645\u0639 \u0627\u0633\u062a\u0628\u0639\u0627\u062f \u0627\u0644\u062e\u0644\u0641\u064a\u0629. \u0627\u0633\u062a\u062e\u062f\u0645 \u0627\u0644\u0641\u0631\u064a\u0642 weighted cross entropy\u060c \u0648\u0645\u0639\u062f\u0644 \u062a\u0639\u0644\u0645 0.0001\u060c \u0648\u062a\u062f\u0631\u064a\u0628\u0627\u064b \u0627\u0645\u062a\u062f \u0625\u0644\u0649 100 epoch \u0645\u0639 \u062a\u062f\u0648\u064a\u0631 \u0627\u0644\u0635\u0648\u0631 \u0648\u0642\u0644\u0628\u0647\u0627 \u0623\u0641\u0642\u064a\u0627\u064b \u0648\u0639\u0645\u0648\u062f\u064a\u0627\u064b. \u0647\u0630\u0647 \u0644\u064a\u0633\u062a \u062a\u0641\u0627\u0635\u064a\u0644 \u062a\u0642\u0646\u064a\u0629 \u0644\u0644\u0632\u064a\u0646\u0629\u060c \u0628\u0644 \u062c\u0632\u0621 \u0645\u0646 \u062a\u0642\u064a\u064a\u0645 \u0642\u0627\u0628\u0644\u064a\u0629 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0644\u0644\u062a\u0643\u0631\u0627\u0631 \u0648\u0627\u0644\u0641\u062d\u0635 \u0642\u0628\u0644 \u0623\u064a \u0627\u0633\u062a\u0639\u0645\u0627\u0644 \u0633\u0631\u064a\u0631\u064a.<\/p>\n
\u0627\u0644\u0623\u0631\u0642\u0627\u0645 \u0627\u0644\u062a\u064a \u064a\u062c\u0628 \u0642\u0631\u0627\u0621\u062a\u0647\u0627 \u0628\u062d\u0630\u0631<\/h2>\n
\u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0628\u0643\u0633\u0644\u060c \u0633\u062c\u0651\u0644 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u062f\u0642\u0629 93.08%\u060c \u0648\u062d\u0633\u0627\u0633\u064a\u0629 74.62%\u060c \u0648\u0646\u0648\u0639\u064a\u0629 93.71%. \u0648\u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u062e\u0644\u0648\u064a\u0629\u060c \u0628\u0644\u063a\u062a \u0627\u0644\u062f\u0642\u0629 \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629 94.58%\u060c \u0648\u0627\u0644\u0627\u0633\u062a\u062f\u0639\u0627\u0621 81.36%. \u0647\u0630\u0647 \u0623\u0631\u0642\u0627\u0645 \u062c\u064a\u062f\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u0627 \u062a\u0643\u0641\u064a \u0648\u062d\u062f\u0647\u0627 \u0644\u0627\u062e\u062a\u0628\u0627\u0631 PD-L1. \u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0644\u0627 \u064a\u0642\u0631\u0631 \u0627\u0644\u0639\u0644\u0627\u062c \u0645\u0646 pixel accuracy\u060c \u0628\u0644 \u0645\u0646 \u0641\u0626\u0629 \u062a\u0642\u0631\u064a\u0631 \u0644\u0647\u0627 \u0623\u062b\u0631 \u0645\u0628\u0627\u0634\u0631 \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u064a\u0636.<\/p>\n
\u0644\u0630\u0644\u0643 \u0627\u062e\u062a\u0628\u0631 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0627\u0644\u062a\u0637\u0627\u0628\u0642 \u0645\u0639 TPS \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u062d\u0627\u0644\u0629. \u0641\u064a \u0639\u064a\u0646\u0629 \u0623\u0648\u0644\u064a\u0629 \u0645\u0633\u062a\u0642\u0644\u0629 \u0645\u0646 30 \u0635\u0648\u0631\u0629\u060c \u0646\u0635\u0641\u0647\u0627 adenocarcinoma \u0648\u0646\u0635\u0641\u0647\u0627 squamous cell carcinoma\u060c \u0643\u0627\u0646 \u0645\u0639\u0627\u0645\u0644 \u0627\u0644\u0627\u0631\u062a\u0628\u0627\u0637 \u0628\u064a\u0646 \u062a\u0642\u062f\u064a\u0631 \u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0648\u062f\u0631\u062c\u0629 \u0627\u0644\u0646\u0645\u0648\u0630\u062c 96.97%. \u0647\u0630\u0647 \u0646\u062a\u064a\u062c\u0629 \u0645\u0634\u062c\u0639\u0629\u060c \u0644\u0643\u0646\u0647\u0627 \u0644\u064a\u0633\u062a \u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u0642\u0635\u0629. \u0641\u0627\u0644\u0645\u0646\u0627\u0637\u0642 \u0627\u0644\u062d\u062f\u064a\u0629 \u0628\u0642\u064a\u062a \u0647\u064a \u0645\u0648\u0636\u0639 \u0627\u0644\u0636\u063a\u0637 \u0627\u0644\u062d\u0642\u064a\u0642\u064a.<\/p>\n
\u0639\u0646\u062f \u062a\u0642\u0633\u064a\u0645 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u0644\u0649 \u062b\u0644\u0627\u062b \u0641\u0626\u0627\u062a TPS\u060c \u0643\u0627\u0646\u062a \u0627\u0644\u062f\u0642\u0629 \u0627\u0644\u0645\u0639\u0644\u0646\u0629 47.16% \u0641\u064a \u0641\u0626\u0629 \u0623\u0642\u0644 \u0645\u0646 1%\u060c \u064895% \u0641\u064a \u0641\u0626\u0629 1 \u0625\u0644\u0649 49%\u060c \u064895% \u0641\u064a \u0641\u0626\u0629 \u0623\u0639\u0644\u0649 \u0645\u0646 50%. \u0648\u0639\u0646\u062f \u062a\u0642\u0633\u064a\u0645\u0647\u0627 \u0625\u0644\u0649 \u0623\u0631\u0628\u0639 \u0641\u0626\u0627\u062a \u0623\u062f\u0642\u060c \u0623\u0635\u0628\u062d\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c 88.3% \u0644\u0623\u0642\u0644 \u0645\u0646 4.9%\u060c \u064890.90% \u0628\u064a\u0646 5 \u064839.99%\u060c \u064866.67% \u0628\u064a\u0646 40 \u064859.99%\u060c \u064871.43% \u0644\u0623\u0639\u0644\u0649 \u0645\u0646 60%. \u0627\u0644\u0631\u0642\u0645 \u0627\u0644\u0630\u064a \u064a\u0646\u0628\u063a\u064a \u0623\u0646 \u064a\u0644\u0641\u062a \u0627\u0646\u062a\u0628\u0627\u0647\u0646\u0627 \u0647\u0648 66.67% \u062d\u0648\u0644 40 \u0625\u0644\u0649 60%. \u0647\u0630\u0647 \u0645\u0646\u0637\u0642\u0629 \u0642\u0631\u0627\u0631 \u0639\u0644\u0627\u062c\u064a\u0629\u060c \u0648\u0644\u064a\u0633\u062a \u0647\u0627\u0645\u0634\u0627\u064b \u0625\u062d\u0635\u0627\u0626\u064a\u0627\u064b.<\/p>\n
\u0627\u0644\u0642\u064a\u0645\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0629: \u062a\u0635\u0639\u064a\u062f \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0635\u0639\u0628\u0629 \u0644\u0627 \u0625\u062e\u0641\u0627\u0624\u0647\u0627<\/h2>\n
\u0627\u0644\u062a\u0635\u0645\u064a\u0645 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0627\u0644\u0645\u0642\u062a\u0631\u062d \u064a\u0639\u0627\u0645\u0644 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0642\u0631\u064a\u0628\u0629 \u0645\u0646 1% \u064850% \u0643\u062d\u0627\u0644\u0627\u062a \u062a\u062d\u062a\u0627\u062c \u0645\u0631\u0627\u062c\u0639\u0629 \u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636. \u0647\u0630\u0627 \u0647\u0648 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0623\u0647\u0645 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629. \u0627\u0644\u0623\u062f\u0627\u0629 \u0644\u0627 \u062a\u064f\u0633\u062a\u062e\u062f\u0645 \u0643\u064a \u062a\u0637\u0645\u0633 \u0627\u0644\u0634\u0643\u060c \u0628\u0644 \u0643\u064a \u062a\u0643\u0634\u0641\u0647 \u0648\u062a\u0648\u062c\u0647\u0647 \u0625\u0644\u0649 \u0627\u0644\u0634\u062e\u0635 \u0627\u0644\u0645\u0633\u0624\u0648\u0644 \u0639\u0646 \u0627\u0644\u062a\u0642\u0631\u064a\u0631.<\/p>\n
\u062a\u0635\u0641 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0633\u064a\u0631 \u0639\u0645\u0644 \u064a\u062d\u062a\u0641\u0638 \u0628\u0627\u0644\u0625\u0646\u0633\u0627\u0646 \u062f\u0627\u062e\u0644 \u0627\u0644\u062d\u0644\u0642\u0629. \u064a\u0645\u0643\u0646 \u0644\u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0631\u0641\u0639 \u0635\u0648\u0631\u0629 H&E \u0648\u0645\u0631\u0627\u062c\u0639\u062a\u0647\u0627 \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 IHC\u060c \u0648\u062a\u062d\u062f\u064a\u062f ROI\u060c \u0648\u062a\u0634\u063a\u064a\u0644 \u0627\u0644\u062e\u0648\u0627\u0631\u0632\u0645\u064a\u0629\u060c \u062b\u0645 \u0641\u062d\u0635 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0639\u0644\u0649 overlay \u064a\u0648\u0636\u062d \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u064a \u0639\u062f\u0651\u0647\u0627 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0623\u0648 \u0633\u0644\u0628\u064a\u0629. \u0628\u0647\u0630\u0647 \u0627\u0644\u0637\u0631\u064a\u0642\u0629 \u064a\u0635\u0628\u062d \u0627\u0644\u0631\u0642\u0645 \u0642\u0627\u0628\u0644\u0627\u064b \u0644\u0644\u0645\u0631\u0627\u062c\u0639\u0629\u060c \u0644\u0627 \u0635\u0646\u062f\u0648\u0642\u0627\u064b \u0623\u0633\u0648\u062f \u064a\u0636\u064a\u0641 TPS \u0625\u0644\u0649 \u0627\u0644\u062a\u0642\u0631\u064a\u0631 \u062f\u0648\u0646 \u062a\u0641\u0633\u064a\u0631 \u0628\u0635\u0631\u064a.<\/p>\n
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\u0642\u0631\u0627\u0621\u0629 \u0646\u0642\u062f\u064a\u0629 \u0645\u062e\u062a\u0635\u0631\u0629<\/h2>\n
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\u0641\u064a \u0627\u0644\u0645\u0642\u0627\u0628\u0644\u060c \u064a\u062c\u0628 \u0623\u0646 \u0646\u0646\u062a\u0628\u0647 \u0625\u0644\u0649 \u062d\u062f\u0648\u062f \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a. \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u062c\u0627\u0621\u062a \u0645\u0646 \u0645\u0635\u062f\u0631 \u0625\u0642\u0644\u064a\u0645\u064a \u0645\u062d\u062f\u062f\u060c \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 assay \u0648\u0645\u0627\u0633\u062d \u0648\u0633\u064a\u0631 \u0639\u0645\u0644 \u0645\u0639\u0631\u0648\u0641\u064a\u0646. \u0646\u0642\u0644 \u0627\u0644\u0623\u062f\u0627\u0621 \u0625\u0644\u0649 \u0645\u062e\u062a\u0628\u0631 \u0622\u062e\u0631 \u064a\u062d\u062a\u0627\u062c \u062a\u062d\u0642\u0642\u0627\u064b \u0645\u062d\u0644\u064a\u0627\u064b: \u0635\u0628\u063a\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629\u060c \u0645\u0627\u0633\u062d\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629\u060c \u0627\u062e\u062a\u0644\u0627\u0641\u0627\u062a \u0641\u064a \u0627\u0644\u062a\u0642\u0637\u064a\u0639\u060c \u0648\u062a\u0628\u0627\u064a\u0646 \u0641\u064a \u0646\u0645\u0637 \u0627\u062e\u062a\u064a\u0627\u0631 ROI. \u0644\u0627 \u062a\u0648\u062c\u062f \u0623\u062f\u0627\u0629 PD-L1 \u0631\u0642\u0645\u064a\u0629 \u062a\u0639\u0628\u0631 \u0647\u0630\u0647 \u0627\u0644\u0641\u0631\u0648\u0642\u0627\u062a \u0628\u0645\u062c\u0631\u062f \u062a\u062b\u0628\u064a\u062a\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u062e\u0627\u062f\u0645.<\/p>\n
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\u0627\u0644\u0645\u0635\u062f\u0631<\/h3>\n
Pathology News: AI driven pre-regulatory validation of PD-L1 analysis in lung cancer<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"\u062f\u0631\u0627\u0633\u0629 \u062d\u062f\u064a\u062b\u0629 \u0639\u0646 \u0623\u062f\u0627\u0629 \u062a\u0639\u0644\u0645 \u0639\u0645\u064a\u0642 \u0645\u0633\u0627\u0639\u062f\u0629 \u0641\u064a \u062d\u0633\u0627\u0628 TPS \u0644\u0627\u062e\u062a\u0628\u0627\u0631 PD-L1 \u0641\u064a \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u0631\u0626\u0629\u060c \u0645\u0639 \u062a\u0631\u0643\u064a\u0632 \u0639\u0645\u0644\u064a \u0639\u0644\u0649 \u0639\u062a\u0628\u0627\u062a 1% \u064850% \u0648\u062f\u0648\u0631 \u0627\u062e\u062a\u0635\u0627\u0635\u064a \u0627\u0644\u0623\u0645\u0631\u0627\u0636 \u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u062d\u062f\u064a\u0629.","protected":false},"author":1,"featured_media":1164,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"csco_singular_sidebar":"","csco_page_header_type":"","csco_page_load_nextpost":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4],"tags":[],"class_list":{"0":"post-1165","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-news","8":"cs-entry"},"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/pathology.digital\/wp-content\/uploads\/2026\/05\/featured_54053.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts\/1165","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1165"}],"version-history":[{"count":0,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/posts\/1165\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=\/wp\/v2\/media\/1164"}],"wp:attachment":[{"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1165"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1165"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pathology.digital\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1165"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}